Target/Analyte:
Linsitinib

Short Name Linsitinib
Description Linsitinib is an experimental drug candidate for the treatment of various types of cancer. It is an inhibitor of the insulin receptor and of the insulin-like growth factor 1 receptor (IGF-1R). This prevents tumor cell proliferation and induces tumor cell apoptosis.

Method/Kits with this Target/Analyte
Method/Kit Description
LC-MS/MS Determination of analyte concentration by LC-MS/MS
Single-Use RED Plate with Inserts (Thermo Scientific: 2034.6) and ICP-MS Single-Use RED Plate with Inserts (Thermo Scientific: 2034.6) followed by mass spectrometry for quantification of compound and determination of: % Free = (Concentration buffer chamber/Concentration plasma chamber) × 100% and % Bound = 100% - % Free.

Studies Utilizing this Target/Analyte
Study Start Date Study Types Description
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