Target/Analyte:
OAT1

Short Name OAT1
Description Oat1 [Slc22a6, originally identified as NKT (novel kidney transporter)] plays a central role in the metabolism and handling of gut microbiome metabolites as well as putative uremic toxins of kidney disease.

The organic anion transporter (OAT) subfamily has a role in handling of common drugs (antibiotics, antivirals, diuretics, nonsteroidal anti-inflammatory drugs), toxins (mercury, aristolochic acid), and nutrients (vitamins, flavonoids).

[Nigam SK, Bush KT, Martovetsky G, et al. The organic anion transporter (OAT) family: a systems biology perspective. Physiol Rev. 2015;95(1):83-123. doi:10.1152/physrev.00025.2013]

Method/Kits with this Target/Analyte
Method/Kit Description
Immunocytochemistry and immunofluorescence protocol (DAPI, FITC, Cy5) Immunocytochemistry (Cy5, DAPI, FITC) used for imaging and observation of HO-1, DNA, OAT4.
Immunocytochemistry and immunofluorescence protocol Immunocytochemistry (ICC) combines anatomical, immunological and biochemical techniques to image discrete components in tissues by using appropriately-labeled antibodies to bind specifically to their target antigens in situ.
Immunocytochemistry and immunofluorescence protocol (DAPI, FITC, Cy5) Immunocytochemistry (Cy5, DAPI, FITC) used for imaging and observation of HO-1, DNA, OAT4.

Studies Utilizing this Target/Analyte
Study Start Date Study Types Description
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