Target/Analyte:
KIM-1 (human)

Short Name KIM-1
Description Kidney injury molecule 1 (KIM-1) is a cell surface receptor that is expressed on kidney epithelial cells and by distinct T cell populations and hepatocytes. In acutely injured kidneys, KIM-1 is thought to confer a phagocytic phenotype on kidney epithelial cells that contributes to recovery by removing debris from cells that died during the injury.
In patients with CKD, on the other hand, elevated KIM-1 expression has been shown to occur close to inflammatory cells and fibrotic tissue. However, whether KIM-1 actively promotes kidney fibrosis has not been resolved..

Method/Kits with this Target/Analyte
Method/Kit Description
Bio-Plex Pro™ RBM Human Kidney Toxicity Panel 1 The Bio-Plex Pro human kidney toxicity panel 1 immunoassay is an all-in-one 1 x 96-well kit that includes premixed magnetic capture beads and detection antibodies, standards, 2-level controls, standard diluent, buffers (blocking, sample dilution, and 10x assay), 10x streptavidin-PE, flat bottom plate/seals, and instructions for the detection of the following analytes: Calbindin Clusterin GST-pi IL-18 KIM-1 MCP-1 Instrument Compatibility Bio-Plex® MAGPIX™ multiplex reader Bio-Plex® 200 system Bio-Plex 3D suspension array system Bio-Plex Pro wash stations
Human Kidney Injury Magnetic Bead Panel 1 (HKI1MAG-99K) Multiplex ELISA kit to detect Calbindin, GST-a, GST-pi, Osteoactivin, TIMP-1, KIM-1, IP-10, Renin, FABP-1, Collagen IV, and TFF-3
Human KIM-1 Kit (MSD: K151JHD-1, K151JHD-2, K151JHD-4) MSD assay kit for Human KIM-1.
Human Serum TIM-1/KIM-1/HAVCR Immunoassay (R&D Systems: DSKM100) Human Serum TIM-1/KIM-1/HAVCR Immunoassay (R&D Systems: DSKM100)
Human TIM-1/KIM-1/HAVCR DuoSet ELISA Assay type: Solid Phase Sandwich ELISA Format: 96-well strip plate Assay Range: 15.6 - 1,000 pg/mL Sufficient Materials: For fifteen 96-well plates*
MILLIPLEX MAP Human Kidney Injury Magnetic Bead Panel 1 - Toxicity Multiplex Assay The analytes available for this multiplex kit are: Calbindin, Collagen IV, Fatty Acid Binding Protein 1 (FABP1), GSTα, IP-10, Kidney Injury Molecule-1 (KIM-1), Osteoactivin, Renin, TFF-3, TIMP-1.
TIM-1 (HAVCR1) Human ELISA Kit (EHHAVCR1) TIM-1 (HAVCR1) Human ELISA Kit from ThermoFisher
Unspecified Not specified by the user

Studies Utilizing this Target/Analyte
Study Start Date Study Types Description
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