Target/Analyte:
Tolcapone

Short Name Tolcapone
Description Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.

Method/Kits with this Target/Analyte
Method/Kit Description
LC-MS/MS Determination of analyte concentration by LC-MS/MS
Single-Use RED Plate with Inserts (Thermo Scientific: 2034.6) and ICP-MS Single-Use RED Plate with Inserts (Thermo Scientific: 2034.6) followed by mass spectrometry for quantification of compound and determination of: % Free = (Concentration buffer chamber/Concentration plasma chamber) × 100% and % Bound = 100% - % Free.

Studies Utilizing this Target/Analyte
Study Start Date Study Types Description
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