Target/Analyte:
Clearance-Testosterone

Short Name CLTSTERONE
Description The clearance is a pharmacokinetic measurement of the volume of plasma from which a substance is completely removed per unit time; the usual units are mL/min. The quantity reflects the rate of drug elimination divided by plasma concentration. In the liver testosterone is metabolized by Cyp3A4.

Method/Kits with this Target/Analyte
Method/Kit Description
Testosterone, IM/MS Testosterone is metabolized by human Cyp 2C9, Cyp 2C19 and Cyp 3A4. The Cyp 3A4 isoenzyme is solely responsible for the human testosterone metabolite 6β-Hydroxytestosterone. In this protocol the level of 6β-Hydroxytestosterone and testosterone found in the liver efflux media is used as a monitor of liver induction or inhibition.
Unspecified Not specified by the user

Studies Utilizing this Target/Analyte
Study Start Date Study Types Description
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