Target/Analyte:
Osteocalcin

Short Name OCL
Description Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein hormone found in bone and dentin. Because it has gla domains, its synthesis is vitamin K dependent. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A.

Method/Kits with this Target/Analyte
Method/Kit Description
Human Bone Panel II Kit (MSD: K15147C) The Human Bone Marker Panel II Kit provides assay-specific components for the quantitative determination of both natural and recombinant human osteocalcin (OCL), osteonectin (ONN), and osteopontin (OPN) in serum and plasma.
Human Osteocalcin Quantikine ELISA ( R&D Systems DSTCN0) Human osteocalcin secretion ELISA
RT-PCR (Applied Biosystems: StepOnePlus and SYBR Green Reaction Mix) Real-time PCR noted in Tuan work. RT-PCR (Applied Biosystems: StepOnePlus and SYBR Green Reaction Mix) Lin et al. Mol. Pharmaceutics 2014) The SYBR Green I dye chemistry uses Applied Biosystems™ SYBR™ Green I dye, a highly specific, double-stranded DNA binding dye, to detect PCR product as it accumulates during PCR cycles. The most important difference between the TaqMan and SYBR Green I dye chemistries is that the SYBR Green I dye chemistry will detect all double-stranded DNA, including non-specific reaction products. A well-optimized reaction is therefore essential for accurate results.

Studies Utilizing this Target/Analyte
Study Start Date Study Types Description
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