Method/Kit:
LC-MS/MS

Measurement Type Mass Spectrometry
Description Determination of analyte concentration by LC-MS/MS

Target/Analytes with this Method/Kit
Target/Analyte Short Name Description
1-OH-Midazolam glucuronide 1-OH-Glu 1-OH-Midazolam glucuronide
1α,25-Dihydroxyvitamin D Calcitriol Calcitriol (INN), also called 1,25-dihydroxycholecalciferol or 1,25-dihydroxyvitamin D3, is the hormonally active metabolite of vitamin D
24,25-Dihydroxyvitamin D 24,25-(OH)2D3 24,25-Dihydroxycholecalciferol, also known as 24,25-dihydroxyvitamin D3 and (24R)-hydroxycalcidiol (abbreviated as 24(R),25-(OH)2D3), is a compound which is closely related to 1,25-dihydroxyvitamin D3, the active form of vitamin D3, but like vitamin D3 itself and 25-hydroxyvitamin D3 is inactive as a hormone both in vitro and in vivo.
24,25-Dihydroxyvitamin D (formation clearance) 24,25-(OH)2D3 Clf Formation Clearance rate of 24,25-(OH)2D3 production
2,4-Dintrophenol 2,4-Dintrophenol In 20 pesticide mixture
25-Hydroxyvitamin D Calcifediol Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick.
4:2 Fluorotelomer sulfonic acid (4:2 FTS) 4:2 FTS 4:2 Fluorotelomer sulfonic acid (4:2 FTS) detected in media or cells.
4-hydroxydiclofenac 4-hydroxydiclofenac 4-hydroxydiclofenac
4-hydroxydiclofenac (Formation Rate) 4-OH-diclofenac (fr) The formation rate of 4-hydrodiclofenac in a study of metabolite formation.
6:2 fluorotelomer sulfonate (6:2 FTS) 6:2 FTS 6:2 fluorotelomer sulfonate (6:2 FTS) detected in media or cells.
6beta-Hydroxytestosterone 6beta-Hydroxytestost 6beta-Hydroxytestosterone
6beta-Hydroxytestosterone (Formation Rate) 6beta-OH-testos (fr) The formation rate of 6beta-Hydroxytestosterone in a study of metabolite formation.
7-Hydroxycoumarin glucuronide 7-Hydroxycoumarin gl 7-Hydroxycoumarin glucuronide
7-Hydroxycoumarin glucuronide (Formation Rate) 7-OH-coum glu (fr) The formation rate of 7-Hydroxycoumarin glucuronide in a study of metabolite formation.
8:2 Fluorotelomer sulfonic acid (8:2 FTS) 8:2 FTS 8:2 Fluorotelomer sulfonic acid (8:2 FTS) detected in media or cells.
Acetaminophen Acetaminophen Acetaminophen
Acetaminophen (Formation Rate) Acetaminophen (fr) The formation rate of Acetaminophen in a study of metabolite formation.
albumin normalized glycochenodeoxycholic acid Normalized GCDC chip albumin normalized to glycochenodeoxycholic acid value
Azinphos Azinphos In 20 pesticide mixture
Benzophenone-4 (BP4) BP4 Benzophenone-4 (BP4) detected in media or cells.
Caffeine Caffeine Caffeine is a chemical found in coffee, tea, cola, guarana, mate, and other products
chenodeoxycholic acid CDCA bile acid
Chlorpyrifos Chlorpyrifos In 20 pesticide mixture
Cholic acid (CA) CA Bile Acid
Colchicine Colchicine Colchicine detected in media or cells.
Coumarin Coumarin Coumarin
Coumarin (Elimination Rate) Coumarin (er) The elimination rate of Coumarin in a study of metabolite formation.
Dexamethasone Dexamethasone Dexamethasone is a type of corticosteroid medication. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis.
Diazinon Diazinon In 20 pesticide mixture
Diclofenac Diclofenac Diclofenac
Diclofenac (Elimination Rate) Diclofenac (er) The elimination rate of Diclofenac in a study of metabolite formation.
Disulfoton Disulfoton In 20 pesticide mixture
Doxorubicin Doxorubicin Doxorubicin, sold under the trade names Adriamycin among others, is a chemotherapy medication used to treat cancer. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used together with other chemotherapy agents. Doxorubicin is given by injection into a vein.
Drug Concentration Drug Concentration Concentration of compound
Drug Recovery RECOVERY
Ethion Ethion In 20 pesticide mixture
Fexofenadine Fexofenadine Fexofenadine
Fexofenadine (Formation Rate) Fexofenadine (fr) The formation rate of Fexofenadine in a study of metabolite formation.
Gentamicin Gentamicin Gentamicin
glycochenodeoxycholic acid GCDC glycine conjugated bile acid
Glycocholic acid (GCA) GCA Bile Acid
Ibuprofen Ibuprofen Ibuprofen detected in media or cell lysate
INDOMETHACIN INDOMETHACIN Synonyms: SID90340917, Indocin, Indometacin, Indomethacin, Desmethyl indomethacin, SID856012, Indocin SR, Indo-Lemmon, Indometacin Farnesil, SID85231093, SID56422212
Internal Standard IS An internal standard for associated analytes. Intended to be associated with target/analyte data points through the MIF-C-assay Assay Well ID.
Linsitinib Linsitinib Linsitinib is an experimental drug candidate for the treatment of various types of cancer. It is an inhibitor of the insulin receptor and of the insulin-like growth factor 1 receptor (IGF-1R). This prevents tumor cell proliferation and induces tumor cell apoptosis.
Metabolomics Metabolomics Metabolomics measured by LC-MS/MS
Methotrexate MTX Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions.
Metoprolol Metoprolol LC ms/ms
Morphine Morphine Concentration of Morphine collected from chip and tested via LCMS.
N-ACETYLASPARTIC ACID NAA Measure of NAA produced by model
Omeprazole Omeprazole LC ms/ms quantiation
Paclitaxel Paclitaxel Compound
para-aminohippuric acid Secretion pAH Secretion Fraction or percent of pAH secreted into the effluent of the collection channel, from the treated channel.
Perfluorobutanoic acid (PFBA) PFBA Perfluorobutanoic acid (PFBA) detected in media via LCMS/MS
Perfluorodecanoic acid (PFDA) PFDA Perfluorodecanoic acid (PFDA)
Perfluoroheptanoic acid (PFHpA) PFHpA Perfluoroheptanoic acid (PFHpA) recovered from cells or media
Perfluorohexanesulfonic acid (PFHxS) PFHxS Perfluorohexanesulfonic acid (PFHxS) detected in media or cells
Perfluorononanoic acid (PFNA) PFNA Perfluorononanoic acid (PFNA) detected in media or cells
Perfluoropentanoic acid (PFPeA) PFPeA Perfluoropentanoic acid (PFPeA) detected in media or cells.
Perfluoroundecanoic acid (PFUnDA) PFUnDA Perfluoroundecanoic acid (PFUnDA) detected in media or cells.
PFBS PFBS concentration or amount of Perfluorobutane sulfonate in culture media or buffer.
PFHxA PFHxA Concentration of PFHxA in culture media
PFOA PFOA Concentration, recovery, or permeability of PFOA (Perfluorooctanoic acid) in a culture system.
PFOS PFOS Concentration or amount of Perfluorooctanesulfonic acid in media or buffer
Phenacetin Phenacetin Compound
Phenacetin (Elimination Rate) Phenacetin (er) The elimination rate of Phenacetin in a study of metabolite formation.
Phenolphthalein Phenolphthalein Phenolphthalein
Phenolphthalein (Elimination Rate) Phenolphthalein (er) The elimination rate of Phenolphthalein in a study of metabolite formation.
Phenolphthalein glucuronide Phenolphthalein gluc Phenolphthalein glucuronide
Phenolphthalein glucuronide (Formation Rate) Pheno glu (fr) The formation rate of Phenolphthalein glucuronide in a study of metabolite formation.
Pioglitazone Pioglitazone Pioglitazone is a medication belonging to the thiazolidinedione class of drugs that are used as adjuncts to diet, exercise, and other diabetes medications to manage type 2 diabetes mellitus.
Polymyxin B PMB For measurement of Polymyxin B (typically drug recovery)
Propranolol Propranolol Propranolol hydrochloride
Proteomics - Human Proteomics Proteomics
Rifampicin Rifampicin Rifampicin detected in media or cells.
Rosiglitazone Rosiglitazone Rosiglitazone is an oral drug that reduces the amount of sugar (glucose) in the blood. It is used for treating patients with type 2 diabetes and is in a class of anti-diabetic drugs called thiazolidinediones.
Streptomycin Streptomycin Streptomycin detected in media or cells
Taurochenodeoxycholic acid (TCDCA) TCDCA Bile Acid
taurocholate TC taurine conjugated bile acid
Taurocholic Acid (TCA) TCA Bile Acid
TENOFOVIR Tenofovir concentration, recovery, or permeability of Tenofovir from a culture system.
Terfenadine Terfenadine Terfenadine
Terfenadine (Elimination Rate) Terfenadine (er) The elimination rate of Terfenadine in a study of metabolite formation.
Testosterone Testosterone Testosterone
Testosterone (Elimination Rate) Testosterone (er) The elimination rate of Testosterone in a study of metabolite formation. The usual units are ng/min/10^6 cells.
Tobramycin Tobramycin Tobramycin detected in media or cells.
Tolcapone Tolcapone Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.
Total Bile Acid Total Bile Acid Bile Acid-LC-MS/MS
Total Bile Acids-LC-MS/MS Bile Acid-Total Bile Acid-LC-MS/MS
Troglitazone Troglitazone Troglitazone is an oral antihyperglycemic agent which acts primarily by decreasing insulin resistance.
Trovafloxacin Trovafloxacin Trovafloxacin is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.
Vincristine Vincristine Vincristine, also known as leurocristine and marketed under the brandname Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer among others.

Studies Utilizing this Method/Kit
Study Start Date Study Types Description
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