Method/Kit:
Single-Use RED Plate with Inserts (Thermo Scientific: 2034.6) and ICP-MS

Supplier ThermoFisher
Measurement Type Mass Spectrometry
Description Single-Use RED Plate with Inserts (Thermo Scientific: 2034.6) followed by mass spectrometry for quantification of compound and determination of: % Free = (Concentration buffer chamber/Concentration plasma chamber) × 100% and % Bound = 100% - % Free.


Target/Analytes with this Method/Kit
Target/Analyte Short Name Description
Cadmium CdCl2 Measurement of Cadmium (II) Chloride
Caffeine Caffeine Caffeine is a chemical found in coffee, tea, cola, guarana, mate, and other products
Cisplatin Cisplatin Cisplatin
Dexamethasone Dexamethasone Dexamethasone is a type of corticosteroid medication. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis.
Doxorubicin Doxorubicin Doxorubicin, sold under the trade names Adriamycin among others, is a chemotherapy medication used to treat cancer. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used together with other chemotherapy agents. Doxorubicin is given by injection into a vein.
Gentamicin Gentamicin Gentamicin
Linsitinib Linsitinib Linsitinib is an experimental drug candidate for the treatment of various types of cancer. It is an inhibitor of the insulin receptor and of the insulin-like growth factor 1 receptor (IGF-1R). This prevents tumor cell proliferation and induces tumor cell apoptosis.
Methotrexate MTX Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions.
Pioglitazone Pioglitazone Pioglitazone is a medication belonging to the thiazolidinedione class of drugs that are used as adjuncts to diet, exercise, and other diabetes medications to manage type 2 diabetes mellitus.
Rosiglitazone Rosiglitazone Rosiglitazone is an oral drug that reduces the amount of sugar (glucose) in the blood. It is used for treating patients with type 2 diabetes and is in a class of anti-diabetic drugs called thiazolidinediones.
Tolcapone Tolcapone Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.
Troglitazone Troglitazone Troglitazone is an oral antihyperglycemic agent which acts primarily by decreasing insulin resistance.
Trovafloxacin Trovafloxacin Trovafloxacin is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.
Vincristine Vincristine Vincristine, also known as leurocristine and marketed under the brandname Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer among others.

Studies Utilizing this Method/Kit
Study Start Date Study Types Description
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