Method/Kit:
Bio-Plex Pro™ RBM Human Kidney Toxicity Panel 1

Supplier Bio-Rad Laboratories
Measurement Type Absorbance
Description The Bio-Plex Pro human kidney toxicity panel 1 immunoassay is an all-in-one 1 x 96-well kit that includes premixed magnetic capture beads and detection antibodies, standards, 2-level controls, standard diluent, buffers (blocking, sample dilution, and 10x assay), 10x streptavidin-PE, flat bottom plate/seals, and instructions for the detection of the following analytes:

Calbindin
Clusterin
GST-pi
IL-18
KIM-1
MCP-1

Instrument Compatibility

Bio-Plex® MAGPIX™ multiplex reader
Bio-Plex® 200 system
Bio-Plex 3D suspension array system
Bio-Plex Pro wash stations

Target/Analytes with this Method/Kit
Target/Analyte Short Name Description
Clusterin (human) CLU NCBI Gene Summary for CLU Gene: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, May 2011].
KIM-1 (human) KIM-1 Kidney injury molecule 1 (KIM-1) is a cell surface receptor that is expressed on kidney epithelial cells and by distinct T cell populations and hepatocytes. In acutely injured kidneys, KIM-1 is thought to confer a phagocytic phenotype on kidney epithelial cells that contributes to recovery by removing debris from cells that died during the injury. In patients with CKD, on the other hand, elevated KIM-1 expression has been shown to occur close to inflammatory cells and fibrotic tissue. However, whether KIM-1 actively promotes kidney fibrosis has not been resolved..

Studies Utilizing this Method/Kit
Study Start Date Study Types Description
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