Method/Kit:
Human Kidney Injury Magnetic Bead Panel 1 (HKI1MAG-99K)

Supplier EMD Millipore
Measurement Type Absorbance
Description Multiplex ELISA kit to detect Calbindin, GST-a, GST-pi, Osteoactivin, TIMP-1, KIM-1, IP-10, Renin, FABP-1, Collagen IV, and TFF-3

Target/Analytes with this Method/Kit
Target/Analyte Short Name Description
Calbindin CLBNDN Calbindin is a calcium-binding protein that acts as an endogenous calcium buffer (Li, Decavel, & Hatton, 1995).
KIM-1 (human) KIM-1 Kidney injury molecule 1 (KIM-1) is a cell surface receptor that is expressed on kidney epithelial cells and by distinct T cell populations and hepatocytes. In acutely injured kidneys, KIM-1 is thought to confer a phagocytic phenotype on kidney epithelial cells that contributes to recovery by removing debris from cells that died during the injury. In patients with CKD, on the other hand, elevated KIM-1 expression has been shown to occur close to inflammatory cells and fibrotic tissue. However, whether KIM-1 actively promotes kidney fibrosis has not been resolved..
TIMP TIMP 1 TIMP metallopeptidase inhibitor 1
TIMP metallopeptidase inhibitor 1 (TIMP-1) TIMP-1 TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms.
Trefoil factor 3 TFF-3 Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfide bonds. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are diverse, including protection of the mucosa, thickening of the mucus, and increasing epithelial healing rates. This gene is a marker of columnar epithelium and is expressed in a variety of tissues including goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Type IV Collagen Collagen IV Collagen IV (ColIV or Col4) is a type of collagen found primarily in the basal lamina.

Studies Utilizing this Method/Kit
Study Start Date Study Types Description
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