Method/Kit:
Unspecified

Measurement Type Unspecified
Description Not specified by the user

Target/Analytes with this Method/Kit
Target/Analyte Short Name Description
Albumin ALB Albumin is the major constituent of serum protein (usually over 50%). It is manufactured by the liver from the amino acids taken through the diet. It helps in osmotic pressure regulation, nutrient transport and waste removal. High levels are seen rarely in liver disease, shock, dehydration, or multiple myeloma. Lower levels are seen in poor diets, diarrhea, fever, infection, liver disease, inadequate iron intake, third-degree burns and edemas or hypocalcemia. Normal Adult Range: 3.2 - 5.0 g/dl Optimal Adult Reading: 4.1
Alkaline Phosphatase ALKP Alkaline phosphatase is an enzyme, or more precisely a family of related enzymes, produced in the bile ducts, intestine, kidney, placenta and bone. An elevation in the level of serum alkaline phosphatase (actually enzyme activity is measured in the clinical laboratory), especially in the setting of normal or only modestly elevated ALT and AST activities, suggests disease of the bile ducts. Serum alkaline phosphatase activity can be markedly elevated in bile duct obstruction or in bile duct diseases such as primary biliary cirrhosis or primary sclerosing cholangitis. Alkaline phosphatase is also produced in bone and blood activity can also be increased in some bone disorders.
Alpha-fetoprotein AFP Human alpha-Fetoprotein Quantikine ELISA Kit: alpha-Fetoprotein (AFP), a member of the albuminoid superfamily, is a fetal/tumor-associated protein that is a marker for certain cancers and congenital defects. Like other members of the albuminoid family, AFP can act as a carrier protein, binding several types of molecules including steroids, bilirubin, fatty acids, retinoids, and flavanoids. Some studies suggest that AFP may also act as a regulator of cell growth and survival.
Bile Efflux BILE Measure of bile effluent by hepatocytes.
Blood Urea Nitrogen BUN The nitrogen component of urea, B.U.N. is the end product of protein metabolism and its concentration is influenced by the rate of excretion. Increases can be caused by excessive protein intake, kidney damage, certain drugs, low fluid intake, intestinal bleeding, exercise or heart failure. Decreased levels may be dur to a poor diet, malabsorption, liver damage or low nitrogen intake. Normal Adult Range: 7 - 25 mg/dl Optimal Adult Reading: 16
CCL2 CCL2 CCL2/JE/MCP-1
Clearance-Testosterone CLTSTERONE The clearance is a pharmacokinetic measurement of the volume of plasma from which a substance is completely removed per unit time; the usual units are mL/min. The quantity reflects the rate of drug elimination divided by plasma concentration. In the liver testosterone is metabolized by Cyp3A4.
Contractile Force CForce Force generated by a muscle contraction
Creatinine Creatinine Serum creatinine is the most widely used functional biomarker of the kidney
CXCL8 CXCL8 C-X-C motif chemokine ligand 8
CYP1A1 CYP1A1 Cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) is involved in phase I xenobiotic and drug metabolism (one substrate of it is theophylline). It is inhibited by fluoroquinolones and macrolides and induced by aromatic hydrocarbons. CYP1A1 is also known as AHH (aryl hydrocarbon hydroxylase). [https://en.wikipedia.org/wiki/CYP1A1]
CYP2C9 CYP2C9 Cytochrome P450 2C9 is an important cytochrome P450 enzyme with a major role in the oxidation of both xenobiotic and endogenous compounds. [https://en.wikipedia.org/wiki/CYP1A1]
CYP3A4 CYP3A4 Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine. It oxidizes small foreign organic molecules, such as toxins or drugs, so that they can be removed from the body. [https://en.wikipedia.org/wiki/CYP3A4]
Cytochrome C CYTC Selective permeabilization of the mitochondrial outer membrane is an integral event in apoptosis resulting in cytochrome c release from the mitochondrial intermembrane space to the cytoplasm. Cytochrome c then triggers activation of caspase proteases via the formation of a complex known as apoptosome.
Drug Recovery RECOVERY
Estimated Glomerular Filtration Rate eGFR A glomerular filtration rate (GFR) is a blood test that checks how well your kidneys are working. Your kidneys have tiny filters called glomeruli. These filters help remove waste and excess fluid from the blood. A GFR test estimates how much blood passes through these filters each minute. A GFR can be measured directly, but it is a complicated test, requiring specialized providers. So GFR is most often estimated using a test called an estimated GFR or eGFR. To get an estimate, your provider will use a method known as a GFR calculator. A GFR calculator is a type of mathematical formula that estimates the rate of filtration. It does this by comparing the results of a blood test that measures creatinine, a waste product filtered by the kidneys, with other information about you.
HAVCR1 HAVCR1 Hepatitis A virus cellular receptor 1
Image IMG Image for later analysis of intensity, morphology, distribution, location, etc.
Image-Hepatocyte HEP Image of hepatocytes for morphology, distribution, etc.
KIM-1 KIM1 KIM-1
KIM-1 (human) KIM-1 Kidney injury molecule 1 (KIM-1) is a cell surface receptor that is expressed on kidney epithelial cells and by distinct T cell populations and hepatocytes. In acutely injured kidneys, KIM-1 is thought to confer a phagocytic phenotype on kidney epithelial cells that contributes to recovery by removing debris from cells that died during the injury. In patients with CKD, on the other hand, elevated KIM-1 expression has been shown to occur close to inflammatory cells and fibrotic tissue. However, whether KIM-1 actively promotes kidney fibrosis has not been resolved..
KIM-1 (rat) KIM1-Rat Rat Kidney Injury Marker 1
Lactate Dehydrogenase LDH Lactic acid dehydrogenase is an intracellular enzyme. Increases in the blood or medium are usually the result of cellular death.
Lactate Dehydrogenase (activity) LDH-activity Lactic acid dehydrogenase is an intracellular enzyme. Increases in the blood or medium are usually the result of cellular death. Activity is measured by the amount of enzyme that catalyzes the conversion of lactate to pyruvate to generate 1.0 μmol of NADH per minute at pH8.8 at 37°C.
Lactate Dehydrogenase-X LDH-X Sperm-producing testes of mammals and some birds contain a unique form of lactate dehydrogenase (EC 1.1.1.27) which is a tetramer composed of C subunits, rather than the A and B subunits of lactate dehydrogenase isozymes 1-5. Immunochemical evidence is presented which confirms the hypothesis that the C subunit is encoded in a separate gene from the A and B polypeptides [Goldberg E. Immunochemical specificity of lactate dehydrogenase-x. Proc Natl Acad Sci U S A. 1971;68(2):349-352.]
N-acetyl-β-D Glucosaminidase NAG A lysosomal enzyme that is abundant in the cells of the proximal kidney tubule, and is excreted in the urine at the time of cell damage
NGAL/Lipocalin-2 NGAL The Lipocalin family comprises a diverse group of mostly secreted soluble proteins that bind hydrophobic ligands and act as transporters, carrying small molecules to specific cells. Lipocalins are related by possessing an 8-stranded beta-barrel structure. Lipocalin-1, also named tear lipocalin (TL), von Ebners gland protein (VEG) and tear pre-albumin, binds a large number of hydrophobic molecules and exhibits cysteine proteinase inhibitor and endonuclear activities. Lipocalin-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), is a component of granules in neutrophils from tissues that are normally exposed to microorganisms and is upregulated during inflammation. Lipocalin-2 can form homodimers and can heterodimerize with the neutrophil gelatinase MMP-9.
Steatosis STEATOSIS Abnormal retention of lipids.
TNF-Alpha TNFA Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons.

Studies Utilizing this Method/Kit
Study Start Date Study Types Description
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